PUBLICATIONS
X. Chen, M.J. McAndrew, A. Lapinaite*. Unlocking the secrets of ABEs: the molecular mechanism behind their specificity. Biochemical Society Transactions (2023).
B.A. Adler, M.I. Trinidad, D. Bellieny-Rabelo, E. Zhang, H.M. Karp, P. Skopintsev, B. Thornton, R.F. Weissman, P.H. Yoon, L. Chen, T. Hessler, A.R. Eggers, D.A. Colognori, R. Boger, E.E. Doherty, C.A. Tsuchida, R.V. Tran, L. Hofman, H. Shi, K.M. Wasko, Z. Zhou, C. Xia, M. Al-Shimary, J. Patel, V. Thomas, R. Pattali, M.J. Kan, A. Vardapetyan, A. Yang, A. Lahiri, M.F. Maxwell, A. Murdock, G. Ramit, H.R. Henderson, R.W. Calvert, R.S. Bamert, G.J. Knott, A. Lapinaite, P. Pausch, J.C. Cofsky, E.J. Sontheimer, B. Wiedenheft, P.C. Fineran, S. Brouns, D. Sashital, B.C. Thomas, C.T. Brown, D.S. Goltsman, R. Barrangou, V. Siksnys, J.F. Banfield, D.F. Savage, J.A. Doudna. CasPEDIA Database: A Functional Classification System for Class 2 CRISPR-Cas Enzymes. EcoEvoRxiv (2023).
G.J. Knott, A. Lapinaite, M.R. O’Connell. Methods special issue: RNA-targeting technologies. Methods (2023).
E.H. Kellogg, J. Gootenberg, O. Abudayyeh, A.S.L. Wong, J.E. Dahlman, A. Lapinaite, C. Myhrvold, C.C. Liu, P.D. Hsu, P. Mali, L.S. Qi. What are the current bottlenecks in developing and applying CRISPR technologies? Cell Systems (2022).
G.J. Knott* & A. Lapinaite*. CRISPR Gets Its Origin Story. CRISPR J (2021)
A. Lapinaite*, G.J. Knott*, C.M. Palumbo, E. Lin-Shiao, M.F. Richter, K.T. Zhao, P.A. Beal, D.R. Liu, J.A. Doudna. DNA capture by a CRISPR-Cas9 guided adenine base editor. Science 369(6503), 566-571 (2020).
M.F. Richter*, K.T. Zhao*, E. Eton, A. Lapinaite, G.A. Newby, B.W. Thuronyi, C. Wilson, L.W. Koblan, J. Zeng, D.E. Bauer, J.A. Doudna, D.R. Liu. Phage-Assisted Evolution of an Adenine Base Editor with Enhanced Cas Domain Compatibility and Activity. Nature Biotechnology 38, 883–891 (2020).
A. Lapinaite, T. Carlomagno, F. Gabel. Small-Angle Neutron Scattering of RNA–Protein Complexes. Methods in Molecular Biology 2113, 165-188 (2020).
A. Lapinaite, J.A. Doudna, J.H.D. Cate. Programmable RNA recognition using a CRISPR-associated Argonaute. PNAS 115(13), 3368-3373 (2018).
Featured in PNAS: In This Issue and in Science: Protein expression, revisited
A. Graziadei, P. Masiewicz, A. Lapinaite, T. Carlomagno. Archaea box C/D enzymes methylate two distinct substrate rRNA sequences with different efficiency. RNA 22(5), 764-7 (2016).
A. Lapinaite, B. Simon, L. Skjaerven, M. Rakwalska-Bange, F. Gabel, T. Carlomagno. The structure of the box C/D enzyme reveals regulation of RNA methylation. Nature 502(7472), 519-23 (2013).
E. Kriukienė, V. Labrie, T. Khare, G. Urbanavičiūtė, A. Lapinaite, K. Koncevičius, D. Li, T. Wang, S. Pai, C. Ptak, J. Gordevičius, S.C. Wang, A. Petronis, S. Klimašauskas. DNA unmethylome profiling by covalent capture of CpG sites. Nature Communications 4, 219 (2013).
C. Ballaré*, M. Lange*, A. Lapinaite*, G.M. Martin, L. Morey, G. Pascual, R. Liefke, B. Simon, Y. Shi, O. Gozani, T. Carlomagno, S.A. Benitah, L. Di Croce. Phf19 links methylated Lys36 of histone H3 to regulation of Polycomb activity. Nature Structural & Molecular Biology 19(12), 1257-65 (2012).
Featured in Nature Structural & Molecular Biology: News & Views
G. Lukinavicius, A. Lapinaite, G. Urbanaviciute, R. Gerasimaite, S. Klimasauskas. Engineering the DNA cytosine-5 methyltransferase reaction for sequence-specific labeling of DNA. Nucleic Acids Research 40(22), 11594-602 (2012).